
The effects of strength training among persons with hand osteoarthritis: a two-year follow-up study
Hand exercise is recommended for hand osteoarthritis (OA) management, but few efficacy studies have been published. The purpose of the study was to determine the effects of two years of whole body strength training and gripper exercise on hand strength, pain, and function in adults with radiographic evidence of hand OA. Older adults (N=55; 71.5+/-6.5 years; 80% female) participated in a two-year, three times per week strength training regimen.

The association of radiographic foot osteoarthritis and radiographic osteoarthritis at other sites
Objective: To quantify the association between radiographic foot osteoarthritis (OA) and radiographic OA at four joints: second distal interphalangeal (DIP), third proximal interphalangeal (PIP), first carpometacarpal (CMC), and the knee.

Smoking and osteoarthritis: is there an association? The Clearwater Osteoarthritis Study
Objective: To evaluate the association between cigarette smoking and the subsequent development of osteoarthritis (OA) at four separate sites: knee, hand, foot and cervical spine.

Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene
Academic Rheumatology, University of Nottingham, UK.
Department of Cardiovascular Sciences, Leicester Cardiovascular Biomedical Research Unit, University of Leicester and National Institute for Health Research, UK.

Osteoarthritis pain and weather
Objective: To evaluate the association between weather (barometric pressure, precipitation and temperature) and pain among individuals with osteoarthritis (OA) (n=154) at the following sites: neck, hand, shoulder, knee and foot.

Older Subjects without Radiographic Knee Osteoarthritis: Weight, Height, and Body Mass Index
Osteoarthritis, the most common form of arthritis, conservatively affects 27 million American adults. While nearly all joints can be affected, knee osteoarthritis is of particular interest as it has the potential to severely limit mobility. Despite its ubiquity, not everyone is affected. Few studies on the characteristics of these persons exist

Joint-specific prevalence of osteoarthritis of the hand
Purpose: To quantify the prevalence of radiographic hand osteoarthritis (OA) among a group of community-dwelling individuals. Joint-specific prevalence rates/100 of radiographic OA of the hand were quantified and reported by age, gender, and dominant hand.

History of acute knee injury and osteoarthritis of the knee: a prospective epidemiological assessment. The Clearwater Osteoarthritis Study
Objective: To evaluate the association between acute joint injury to the knee and knee osteoarthritis (OA).
Design: Prospective cohort. Sample size = 1,436. Men and women aged 40 years and older participating in the population-based Clearwater Osteoarthritis Study (1988-current) with biennial physical exams including serial radiographs. Radiologically confirmed knee OA = 27%; self-reported knee injury = 11%. Lawrence and Kellgren ordinal scale was used to determine radiological evidence of the study outcome, knee OA. Self-reported history of knee injury was used to determine the study exposure.

Exercise and osteoarthritis: are we stopping too early? findings from the Clearwater Exercise Study
The value of exercise for people with knee osteoarthritis (OA) receives continuing consideration. The optimal length of study follow-up time remains unclear. A group of individuals with knee OA participating in an exercise intervention was followed for 2 years. The authors quantified the change in knee-pain scores during Months 1-12 and during Months 13-24. Eleven individuals with radiographic knee OA and knee-pain scores of 2+ were evaluated. Pain scores were collected weekly from participants who exercised three times a week.

Exercise and hand osteoarthritis symptomatology: a controlled crossover trial
Study design: Randomized Clinical Trial.
Introduction: Hand exercises have been recommended as treatment for hand osteoarthritis (OA) but research evidence is sparse.
Purpose of the study: To investigate effects of daily 16-week home-based hand exercise among persons with hand OA.

The effects of strength training among persons with hand osteoarthritis: a two-year follow-up study
Hand exercise is recommended for hand osteoarthritis (OA) management, but few efficacy studies have been published. The purpose of the study was to determine the effects of two years of whole body strength training and gripper exercise on hand strength, pain, and function in adults with radiographic evidence of hand OA. Older adults (N=55; 71.5+/-6.5 years; 80% female) participated in a two-year, three times per week strength training regimen.

The association of radiographic foot osteoarthritis and radiographic osteoarthritis at other sites
Objective: To quantify the association between radiographic foot osteoarthritis (OA) and radiographic OA at four joints: second distal interphalangeal (DIP), third proximal interphalangeal (PIP), first carpometacarpal (CMC), and the knee.

Smoking and osteoarthritis: is there an association? The Clearwater Osteoarthritis Study
Objective: To evaluate the association between cigarette smoking and the subsequent development of osteoarthritis (OA) at four separate sites: knee, hand, foot and cervical spine.

Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene
Academic Rheumatology, University of Nottingham, UK.
Department of Cardiovascular Sciences, Leicester Cardiovascular Biomedical Research Unit, University of Leicester and National Institute for Health Research, UK.

Osteoarthritis pain and weather
Objective: To evaluate the association between weather (barometric pressure, precipitation and temperature) and pain among individuals with osteoarthritis (OA) (n=154) at the following sites: neck, hand, shoulder, knee and foot.

Older Subjects without Radiographic Knee Osteoarthritis: Weight, Height, and Body Mass Index
Osteoarthritis, the most common form of arthritis, conservatively affects 27 million American adults. While nearly all joints can be affected, knee osteoarthritis is of particular interest as it has the potential to severely limit mobility. Despite its ubiquity, not everyone is affected. Few studies on the characteristics of these persons exist

Joint-specific prevalence of osteoarthritis of the hand
Purpose: To quantify the prevalence of radiographic hand osteoarthritis (OA) among a group of community-dwelling individuals. Joint-specific prevalence rates/100 of radiographic OA of the hand were quantified and reported by age, gender, and dominant hand.

History of acute knee injury and osteoarthritis of the knee: a prospective epidemiological assessment. The Clearwater Osteoarthritis Study
Objective: To evaluate the association between acute joint injury to the knee and knee osteoarthritis (OA).
Design: Prospective cohort. Sample size = 1,436. Men and women aged 40 years and older participating in the population-based Clearwater Osteoarthritis Study (1988-current) with biennial physical exams including serial radiographs. Radiologically confirmed knee OA = 27%; self-reported knee injury = 11%. Lawrence and Kellgren ordinal scale was used to determine radiological evidence of the study outcome, knee OA. Self-reported history of knee injury was used to determine the study exposure.

Exercise and osteoarthritis: are we stopping too early? findings from the Clearwater Exercise Study
The value of exercise for people with knee osteoarthritis (OA) receives continuing consideration. The optimal length of study follow-up time remains unclear. A group of individuals with knee OA participating in an exercise intervention was followed for 2 years. The authors quantified the change in knee-pain scores during Months 1-12 and during Months 13-24. Eleven individuals with radiographic knee OA and knee-pain scores of 2+ were evaluated. Pain scores were collected weekly from participants who exercised three times a week.

Exercise and hand osteoarthritis symptomatology: a controlled crossover trial
Study design: Randomized Clinical Trial.
Introduction: Hand exercises have been recommended as treatment for hand osteoarthritis (OA) but research evidence is sparse.
Purpose of the study: To investigate effects of daily 16-week home-based hand exercise among persons with hand OA.
- The effects of strength training among persons with hand osteoarthritis: a two-year follow-up study
- The association of radiographic foot osteoarthritis and radiographic osteoarthritis at other sites
- Smoking and osteoarthritis: is there an association? The Clearwater Osteoarthritis Study
- Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene
- Osteoarthritis pain and weather
- Older Subjects without Radiographic Knee Osteoarthritis: Weight, Height, and Body Mass Index
- Joint-specific prevalence of osteoarthritis of the hand
- History of acute knee injury and osteoarthritis of the knee: a prospective epidemiological assessment. The Clearwater Osteoarthritis Study
- Exercise and osteoarthritis: are we stopping too early? findings from the Clearwater Exercise Study
- Exercise and hand osteoarthritis symptomatology: a controlled crossover trial
- Effect of regular exercise on the radiographic progression of foot osteoarthritis
Peer Reviews
Welcome to our curated collection of medical research. Here, you will find peer-reviewed studies exploring how lifestyle, genetics, weather, and targeted exercise impact osteoarthritis in your hands, knees, and feet, helping you make informed health choices.
Discover the trusted science behind how weight management, past joint injuries, and smoking relate to your everyday health.
Explore these expert findings to better understand your joint symptoms and discover effective ways to keep moving comfortably.